The Ottawa Hospital and Regional Hepatitis Program provides care for over 4000 hepatitis C virus (HCV)-infected patients in Eastern Ontario and Western Quebec, Canada. We also follow approximately 750 hepatitis B virus (HBV)-infected individuals. Our multidisciplinary team maintains a focus on providing treatment for patients who face barriers to care including those living with HIV, mental health illness, substance abuse, poverty and language barriers. Our clinical and research teams are linked with other chronic disease medical disciplines including gastroenterology and hepatology, psychology and psychiatry, endocrinology and social work.